Chinese Journal of Modern Applied Pharmacy 2021 Vol. Issue 10

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中国现代应用药学
Chinese Journal of Modern Applied Pharmacy

Year 2021

Issue 10

Structural Modification and SAR Study of 3-Aryl-5-pyrazol-1,2,4-oxadiazole Derivatives as HIF-1 Inhibitor (3-芳基-5-吡唑基-1,2,4-噁二唑类HIF-1抑制剂的结构优化与构效关系研究)

LIU Yao, LI Shan, QIU Ni, HU Yongzhou, CAO Ji, SHENG Rong, College of Pharmaceutical Sciences, Zhejiang University

.................. page:1153-1160

Simultaneous Determination of Twenty-one Trace Heavy Metal Elements in Cod Liver Oil Using ICP-MS (ICP-MS同时测定鱼肝油中21种重金属元素残留量)

LIANG Jianmou, WANG Yun, Zhejiang Institute for Food and Drug Control, NMPA Key Laboratory for Core Technology of Generic Drug Evaluation, Key Laboratory of Drug Contacting Materials Quality Control of Zhejiang Province

.................. page:1161-1165

Protective Effect of Tanshinone ⅡA on Inflammatory Chondrocytes by Inhibiting PI3K/AKT/NF-κB Pathway (丹参酮ⅡA抑制PI3K/AKT/NF-κB通路对炎性软骨细胞的保护作用)

MENG Rudan, HU Zhangjie, MAO Qiang, Hangzhou Fuyang Orthopedic Hospital of Traditional Chinese Medicine, School of Pharmacy, Zhejiang Chinese Medicine University, The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine)

.................. page:1166-1173

Effects of Ghrelin Receptor Antagonist on Regulation of Liver Function and Protection of Vascular Function in Diabetic Rats (Ghrelin受体拮抗剂对糖尿病大鼠肝功能的调节及血管功能的保护作用)

WANG Xiaojun, ZHANG Yanqiu, ZHAI Tie, Chengde Central Hospital

.................. page:1174-1180

Study on Effect of Polygonatum Polysaccharide on Glycolipid Metabolism in Type 2 Diabetic Rats and Its Mechanism (玉竹多糖对2型糖尿病大鼠糖脂代谢的影响及机制研究)

ZHOU Jun, HUI Xiaoliang, MAO Ying, LU Peiying, Department of Geriatrics, Sandun Hospital District of Zhejiang Hospital

.................. page:1181-1187

Study on Effect and Its Mechanism of Konjac Glucomannan on the Reversal of 5-Fluorotracicl Resistance in Colorectal Cancer (魔芋葡甘露聚糖逆转大肠癌5-氟尿嘧啶耐药的作用及其机制研究)

LU Miaojiong, CHU Weijian, Hangzhou Hospital of Traditional Chinese Medicine

.................. page:1188-1194

Preparation of Ultrasmall Blue Lysine-genipin Nanoparticles for Glioma Cell Staining (蓝色超小赖氨酸-京尼平纳米粒制备及肿瘤细胞染色)

SONG Xiaojie, LI Miaomiao, LYU Qiyan, CUI Huifang, LIU Hongmin, School of Life Sciences, Zhengzhou University, Collaborative Innovation Center of New Drug Research and Safety Evaluation of Henan Province

.................. page:1195-1200

Effects of Different Fractions of Tannic Acid as the Raw Material on the Dissolution Time of Berberine Tannate Pellicles (鞣酸不同级分作为合成原料对鞣酸小檗碱膜溶化时限的影响)

ZHANG Zhi, QIAO Delong, LI Weimin, ZHANG Zheng, LU Ying, XU Xiaoshan, DENG Yueting, Gansu Longshenrongfa Pharmaceutical Industry Co., Ltd., Gansu Key Laboratory of Traditional Chinese Medicine Solid Dispersible Preparation

.................. page:1201-1204

Formulation Optimization of Leonurine Lipid Nanoparticles by Box-Behnken Response Surface Methodology (Box-Behnken响应面法优化益母草碱脂质纳米粒处方)

ZHU Bo, Hwa Mei Hospital, University of Chinese Academy of Sciences

.................. page:1205-1210

Determination of Eight Quinolones Residues in Chicken by Online Clean-up-liquid Chromatography-tandem Mass Spectrometry (在线净化-液质联用法测定鸡肉中8种喹诺酮类兽药残留)

ZHOU Xia, CHEN Bilian, CHEN Wanqin, LIU Zhu, JIN Shaoqiang, DING Yuqi, CHEN Jingyan, WANG Feng, Zhejiang Institution of Food and Drug Control

.................. page:1211-1217

Determination of Aflatoxin in Huoxiang Zhengqi Liquid by Automatic Solid Phase Extraction with HPLC and on Line Post Column Photochemical Derivatization (自动固相萃取-HPLC-在线柱后光化学衍生法测定藿香正气水中黄曲霉毒素)

CHEN Zongliang, ZHOU Lingna, ZHAO Jingfang, JIANG Shipeng, CHEN Guiqian, SHEN Zibo, Jinhua Institute for Food and Drug Control

.................. page:1218-1221

jing du nian ci qu mi lian chuan bei zuo zuo gao zhi shang xiao hua dao chu xue 1 li (京都念慈菴蜜炼川贝枇杷膏致上消化道出血1例)

GU Tongtong, ZHANG Hang, ZHANG Jun, FANG Huan, FANG Zhonghong

.................. page:1222-1223

ka rui li zhu dan kang zhi mian yi jian cha dian yi zhi ji xiang guan xing fei yan 1 li (卡瑞利珠单抗致免疫检查点抑制剂相关性肺炎1例)

ZHANG Meiling

.................. page:1224-1225

zhu she yong li fu ping zhi yan kuang yan di teng tong 1 li (注射用利福平致眼眶、眼底疼痛1例)

AN Yan, DONG Jingru, TAO Xiaoqing, ZHENG Zuo, XIE Hua

.................. page:1226-1227

Application of Hospital-based Health Technology Assessment in the Assessment and Selection of Macrolides (医院卫生技术评估在大环内酯类抗菌药物遴选评价中的应用)

QIU Bo, YANG Haotian, SONG Haojing, DU Runxuan, DONG Zhanjun, Hebei General Hospital

.................. page:1228-1236

Exploration of Standardized Training System for Pharmacists in Preparation Posts in Hospital (医院制剂岗位药师规范化培训体系的探索)

LI Xiaoqiang, LI Qian, ZHAO Qingwei, ZHENG Dongsheng, Department of Clinical Pharmacy, The First Affiliated Hospital, College of Medicine, Zhejiang University

.................. page:1237-1240

Problems and Countermeasures of Funds Management of Drug Clinical Trial Projects (药物临床试验经费管理中的问题与对策)

CAI Yuan, XIONG Jianhua, JIN Lijun, RAO Yuefeng, Wenzhou People’s Hospital, The First Affiliated Hospital, College of Medicine, Zhejiang University

.................. page:1241-1244

Research Progress of Chuanxiong Rhizoma-Gastrodiae Rhizoma on Prevention and Treatment of Migraine (川芎-天麻药对防治偏头痛的研究进展)

CHANG Lulu, ZENG Guirong, LIU Dingding, WANG Jingru, Guizhou University of Traditional Chinese Medicine, Hunan Provincial Research Center for Safety Evaluation of Drugs/Hunan Key Laboratory of Pharmacodynamics and Safety Evaluation of New Drugs

.................. page:1245-1250

Research Progress of Liposomes Coated with Chitosan for Drug Delivery (壳聚糖包覆脂质体递药系统的研究进展)

CHEN Yue, WANG Kun, ZHANG Linglin, State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, National Demonstration Center for Experimental Stomatology Education, West China School of Stomatology, Sichuan University

.................. page:1251-1256

Advances in the Evaluation Strategy of Allergenicity of Multi-component Biochemical Drugs (多组分生化药致敏性评价策略研究进展)

WU Yinnan, WANG Yuxin, YANG Qitao, XU Peng, ZHANG Siqi, ZONG Weifeng, MENG Changhong, SHI Qingshui, LU Yihong, Department of Pharmaceutical Analysis, Xuzhou Medical University, Jiangsu Institute for Food and Drug Control, China Pharmaceutical University

.................. page:1257-1262

Research Progress and Application Prospect of Preparations Made by 3D Printing (3D打印制剂的研究进展和应用前景)

YI Shaoling, CHEN Lingli, Experiment and Practice Training Center, Guangdong Food and Drug Vocational College

.................. page:1263-1268

Research Progress on the Improving Effect of Cinnamon Extract and Its Active Components on Type 2 Diabetes (肉桂提取物及其活性成分对2型糖尿病改善作用的研究进展)

WANG Baitao, YANG Wenling, CHEN Guocan, LIU Dehai, YANG Shuhao, Institute of Biology Co., Ltd., Henan Academy of Science

.................. page:1269-1274

Application of Amino Acids in Structural Modification of Active Ingredients of Traditional Chinese Medicine with Antitumor Effects (氨基酸在抗肿瘤中药有效成分结构修饰中的应用)

HUANG Zhiyong, GUO Yihua, HUANG Zhen, LI Rongdong, School of Pharmacy, Hunan University of Chinese Medicine

.................. page:1275-1280

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