Chinese Journal of Modern Applied Pharmacy 2018 Vol. Issue 12

Application and Discussion on Ethical Question of CRISPR-Cas9 Gene Editing Technique in Medical Research (基因编辑技术(CRISPR-Cas9)在医学领域的应用及其相关伦理问题思考)

CUI Jianzhou, LIM Lina H.K., SHEN Hanming, National University of Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Life Sciences Institute, National University of Singapore, Graduate School for Integrative Sciences and Engineering

.................. page:1755-1760

Zebrafish Model of New Drug Early Evaluation Established by Ascorbic Acid and All-trans Retinoic Acid (抗坏血酸联合全反式维甲酸建立斑马鱼新药早期评价模型的研究)

GAO Xucong, SUN Chengying, ZHANG Yun, HE Qiuxia, SHEN Xiuping, Tianjin Institute of Pharmaceutical Research New Drug Evaluation Co., Ltd., Tianjin Engineering Research Center of Drug Preclinical Assessment Technology, Shandong Province Biology Institute of Shandong Academy of Sciences

.................. page:1761-1764

Protective Effects of Berberine Hydrochloride on the Intestinal Mucosal Mechanical Barrier in Mice with Ulcerative Colitis (盐酸小檗碱对溃疡性结肠炎小鼠结肠黏膜机械屏障的保护作用)

SHEN Yan, WANG Zhangliu, ZHENG Huajun, ZHONG Jihong, XU Lei, JIANG Xianghong, NI Siyi, LI Si, Department of Gastroenterology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Deportment of Pediatrics, Tongde Hospital of Zhejiang Province

.................. page:1765-1770

Effect of Berbamine on Migration and Invasion of Human Liver Cancer SMMC-7721 Cells (小檗胺对肝癌SMMC-7721细胞侵袭转移的影响)

YU Binbin, QIAN Jin’e, CAO Jianbo, The Affliated Zhangjiagang Hospital of Soochow University, Department of Pharmacy, The Affliated Zhangjiagang Hospital of Soochow University, Center of Translational Medicine

.................. page:1771-1775

ben kan 2018 nian du te yao shen gao zhuan jia ming dan (本刊2018年度特邀审稿专家名单)

.................. page:1775

Effect of 1-Methyltryptophan on the Activation of Microglia in Rat Model of Cerebral Ischemia Reperfusion (1-甲基色氨酸对大鼠脑缺血再灌注模型小胶质细胞活化的干预作用)

YANG Yi, HAN Chenyang, GUO Li, GUAN Qiaobing, The Second Hospital of Jiaxing

.................. page:1776-1781

Embryo and Fetal Developmental Toxicity Study of Neohesperidin in Rats (新橙皮苷对大鼠胚胎-胎仔发育的毒性研究)

SHAO Yanfei, LIN Chunqin, QIAN Renyun, SHEN Xiaofei, YUAN Chenxing, WANG DANDan, DAI Jielu, WENG Qinjie, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Center for Drug Safety Evaluation and Research of Zhejiang University

.................. page:1782-1785

Preparation and Characterization of Nimodipine Solid Dispersion (尼莫地平固体分散体的制备及其理化性质表征)

LU Zhenju, LIU Yi, Ashland China Holding Co., Ltd.

.................. page:1786-1791

Analysis of the Corrosion Degree of Drugs on the Inner Surface of Glass Injection Bottle by SEM-EDS (SEM-EDS解析药物对玻璃注射剂瓶内表面的侵蚀程度)

CHEN Chao, SHI Pei, CHENG Lei, ZI Xiaowei, WANG Guoqin, YU Hui, Zhejiang Insititute for Food and Drug Control, Key Laboratory of Drug Contacting Materials Quality Control of Zhejiang Provincial, Anhui Insititute for Food and Drug Control

.................. page:1792-1796

Content Determination of Six Alkaloids in Fengshigutong Tablet by SPE-HPLC (SPE-HPLC测定风湿骨痛片中6种生物碱类物质的含量)

SHI Yuhua, HUANG Wenkang, HUANG Qinwei, ZHANG Wenting, ZHAO Weiliang, Zhejiang Medical University, Zhejiang Institute for Food and Drug Control

.................. page:1797-1800

Simultaneous Determination of Five Active Components in Xiaoyanlidan Tablets by HPLC (HPLC同时测定消炎利胆片中5种活性成分的含量)

ZHOU Zhengdao, ZHANG Li, ZHOU Huiyun, JIANG Jing, HUANG Ping, Jiangxi Medical College

.................. page:1801-1804

Effects of Yiqi Bushen Formula-containing Serum on Proliferation and Metastasis of Human Gastric Cancer Cell SGC-7901 and CD44~+EpCAM~+ Double Positive Cancer Stem Cells Ratio (益气补肾方含药血清对人胃癌细胞SGC-7901增殖转移及CD44~+EpCAM~+干细胞比例的影响)

LIU Yunxia, XU Yefeng, YAO Yongwei, WANG Yiqing, JIANG Shenjun, WANG Na, JIA Zhen, Department of Oncology, Hangzhou Third Hospital, Zhejiang Chinese Medical University

.................. page:1805-1810

Antihypertensive Effect and Mechanism of Dendrobii Officinalis Caulis Extract by Different Extraction Methods in Spontaneously Hypertensive Rats (不同方法提取的铁皮石斛提取物对自发性高血压大鼠的降压作用及其机制研究)

MA Jinzhen, ZHAO Wenhui, NIE Xiaojing, WU Yue, CHEN Yu, CHEN Xuan, WU Renzhao, Zhejiang Institute of Traditional Chinese Medicine, Zhejiang Chinese Medical University

.................. page:1811-1816

Anti-inflammatory Activity of Swertiamarin and Its Effect on the Expression of NF-κB Pathway-related Factors p65 and IKK-α (獐牙菜苦苷的抗炎活性及其对NF-κB通路相关因子p65和IKK-α表达的影响)

WANG Junyan, TONG Yeling, ZHAO Wenhui, Zhejiang Hospital, Zhejiang Academy of Traditional Chinese Medicine

.................. page:1817-1820

Preliminary Study on the Mechanism of Timosaponin on Cerebral Ischemia-reperfusion Injury in Rats (知母皂苷对大鼠局灶性脑缺血/再灌注损伤的保护作用)

DING Ling, HU Yi, LIU Jie, LI Yan, ZHANG Zuowen, The Central Hospital of Jiangjin, Jiangjin Central Hospital Affiliated to Chongqing Medical University, Chongqing Medical and Pharmaceutial College

.................. page:1821-1825

Optimization of Fagopyrum Dibotrys(D.Don) Hara Extraction Technology Based on Multi-objective Genetic Algorithm (多目标遗传算法优化金荞麦的提取工艺)

ZHAO Yanjun, XIE Shengyang, ZHANG Xiaoxia, LIU Yuan, WU Fan, CAI Tiantian, WU Qiaofeng, The First Affiliated Hospital of Zhejiang Chinese Medicial University, College of Pharmacy, Zhejiang Chinese Medical University

.................. page:1826-1830

Research on Chrysanthemi Indici Flos Standard Decoction (野菊花饮片标准汤剂的研究)

TIAN Wei, ZHEN Yaqin, GAO Le, FAN Shuaishuai, LI Junshan, NIU Liying, Hebei University of Chinese Medicine, Hebei TCM Formula Granule Engineering & Technology Research Center, TCM Formula Granule Research Center of Hebei Province University, Shineway Pharmaceutical Group Ltd.

.................. page:1831-1836

Effect of Different Decoction Models of Automatic Herb Decoction Machine on the Quality of Stroke Decoction (煎药机不同煎煮模式对痰湿瘀阻型中风病汤剂质量的影响)

ZHANG Chunyan, CHENG Ruizhen, LIU Hai, ZHAO Jing, LI Yue, Tianjin Binhai New Area of Traditional Chinese Medicine Hospital

.................. page:1837-1841

Study on Network Target Prediction and Action Mechanism of Zengye Decoction (增液汤的网络靶标预测及作用机制研究)

LI Yuewen, LIU Zhiqiang, WANG Bolong, School of Chemical and Biological Engineering, Yichun University

.................. page:1842-1848

Textual Research on the Legal Medicinal Plants Which from Casuarinaceae to Urticaceae (木麻黄科至荨麻科法定药用植物基源考证)

YI Ze, HUANG Qinwei, ZHAO Weiliang, Zhejiang Institute for Food and Drug Control

.................. page:1849-1854

Comparative Study on the Calyx Kaki and Its Immature Products (柿蒂及其未成熟品的鉴别研究)

WANG Shaohua, MI Wenjia, WANG Yang, Zhejiang Int’l Herbal Medicine Co., Ltd.

.................. page:1855-1858

Chemical Constituents Study of Lycopodium Japonicum (石松的化学成分研究)

WANG Haiying, YANG Ji, LIU Xin, ZHANG Jiantai, ZHU Guoyuan, Taizhou Municipal Hospital, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology

.................. page:1859-1864

Effect of Drug Pair of Fritillaria Cirrhosa-Eriobotryae Folium on Plasma Pharmacokinetics of Three Flavonoids from Eriobotryae Folium (川贝母-枇杷叶配伍对枇杷叶中3种黄酮成分血浆药动学的影响)

LI Tianxue, HU Yutao, WEI Xiao, CHU Chaosen, Lianyungang TCM Branch of Jiangsu Union Technical Institute, Lianyungang Common Technological Center for Drug Research and Development

.................. page:1865-1869

Study on Improvement of Quality Standard of Kebai Mixture (克白合剂质量标准提升研究)

HUANG Qiaoling, TONG Juhua, LUO Sucai, WU Jingyao, WANG Xun, The Third People’s Hospital of Hangzhou, Zhejiang Research Institute of Traditional Chinese Medicine

.................. page:1870-1873

Content Determination of Quercitrin in Naoxinqing Crude Drug and Tablets by HPLC (HPLC测定脑心清流膏及其片剂中槲皮苷的含量)

SU Shiyun, GUO Haibiao, LI Chuyuan, WANG Deqin, HUANG Yan, KUANG Yanhui, CAI Yuedong, Guangzhou Baiyun Mountain and Hutchison Whampoa Ltd.

.................. page:1874-1877

Simultaneous Determination of Five Major Flavonoids in Tetrastigma Hemsleyanum by HPLC (HPLC同时测定三叶青中5种黄酮类成分的含量)

LIU Shuaiying, ZHANG Xiaoqin, WANG Huiyu, YUAN Zhouxin, LEI Houxing, NI Jingli, Lishui Inspection Institute for Food and Drug & Quality and Technology Control, Lishui Hospital of Traditional Chinese Medicines

.................. page:1878-1880

Research on Treatment Adherence and Economy Burden in Patients with Systemic Lupus Erythematosus in Shanghai (上海市系统性红斑狼疮患者的治疗依从性及经济负担状况分析)

ZHANG Le, WANG Huijing, LIU Zhe, YE Shuang, WANG Huiru, LU Minhua, LU Guohong, South Campus, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Department of Pharmacy, South Campus, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Department of Rheumatology, Department of Physical Education, Shanghai Jiao Tong University, Department of Rheumatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University

.................. page:1881-1885

Systematic Review of Budesonide Combined with Terbutaline on the Clinical Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease (布地奈德联合特布他林雾化吸入对AECOPD临床治疗的系统评价)

XIE Wenjia, WU Jianjun, Gansu University of Chinese Medicine

.................. page:1886-1889

Pharmaceutical Care for One Patient with AIDS Accompanied by Autoimmune Hemolytic Anemia and a Variety of Opportunistic Infection (1例艾滋病伴自身免疫性溶血性贫血及多种机会性感染患者的药学监护)

ZHANG Jianping, WANG Xiaofeng, CHEN Lin, The First Hospital of Lanzhou University, Department of Pharmacy, The First Hospital of Lanzhou University, Department of Infectious Diseases

.................. page:1890-1893

Literature Review of 24 Cases with Methimazole-induced Cholestatic Liver Injury (24例甲巯咪唑致胆汁淤积性肝损伤文献分析)

XIE Xingxing, FAN Ling, YE Yun, XIONG Yuxia, The Affiliated Hospital of Southwest Medical University, Department of Pharmacy, The Affiliated Hospital of Southwest Medical University, Drug Clinical Trail Institution, School of Pharmacy, Southwest Medical University

.................. page:1894-1897

Study on Declaration of Excipients in the Labelling and Package Leaflet of Medicinal Products (药品标签和说明书中药用辅料信息的规范标注)

CHEN Lei, Chinese Pharmacopoeia Commission

.................. page:1898-1901

Practice and Experience of Decreasing Drug Proportion by a Series of Measures of Circuit Breaker on the Key Monitoring Drugs (重点监控药品实施“熔断”机制等措施降低医院药占比的实践与体会)

CHEN Kaixia, ZHAO Guangyu, HUANG Jixun, Department of Pharmacy, Jingjiang People’s Hospital

.................. page:1902-1905