Chinese Journal of Antibiotics 2018 Vol. Issue 1

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中国抗生素杂志
Chinese Journal of Antibiotics

Year 2018

Issue 1

Gut microbiota: The effects of health, illness and medicines (肠道菌群与健康、疾病和药物作用的影响)

Liu Chang-xiao, New Drug Evaluation Research Center, Tianjin Institute of Pharmaceutical Research, State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Binhai Research Center for Food and Drug Regulatory Science

.................. page:1-14

The current state and R&D strategies of antibiotics combinations against drugresistant bacteria in China and aboard (国内外抗耐药复方抗生素研发的现状及开发策略)

Gong Mei-fang, Fu Si-hai, Guangzhou Welman New Drug R&D Co., Ltd

.................. page:15-21

Development and application of a high-throughput screening assay for inhibitors of human FK506 binding protein 52 (以FK506结合蛋白52为靶点的高通量药物筛选模型的建立及应用)

Li Ruo-lan, Zhao Feng, Xu Yan, Wang Xin-rong, Zheng Hai-zhou, Gou Xiao-jun, Lu Xin-hua, Zhang Xue-xia, Chu Yi-wen, Zheng Zhi-hui, New Drugs Research & Development Limited Liability Company of North China Pharmaceutical Group Corporation, National Engineering Research Center of Microbial Medicine, Hebei Industry Microbial Metabolic Engineering & Technology Research Center, Shijiazhuang Engineering Laboratory for New Drugs Screening, Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University

.................. page:22-27

Genome guided investigation of metabolites of the strain Streptomyces mobaraensis (基因组信息指导下茂源链霉菌代谢产物研究)

Wang Shan-shan, Guo Wen-qiang, He Ning, Qi Xin, Xie Yun-ying, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College

.................. page:28-34

Identification of fungus F956 and its metabolites with PTP1B inhibitory activity (PTP1B抑制活性真菌F956的鉴定和代谢产物研究)

Huo Pei-yuan, Xu Yan, Lin Jie, Li Ye-ying, Zheng Hai-zhou, Shen Wen-bin, Ren Xiao, Shi Ying, Cui Xiao-lan, Zheng Zhi-hui, Lu Xin-hua, Zhang Xue-xia, National Engineering Research Center of Microbial Medicine, Hebei Industry Microbial Metabolic Engineering & Technology Research Center, New Drug Research & Development Company of NCPC

.................. page:35-39

Taxonomic studies on a fidaxomicin-producing strain N12W0304 isolated from the medicinal plant (产非达霉素药用植物内生放线菌N12W0304的分类鉴定)

Ding Yan-bo, Mu Yun-long, Huo Pei-yuan, Shan Yue-qi, Xu Yan, Lu Xin-hua, Zhang Xue-xia, National Engineering Research Center of Microbial Medicine, Hehei Industry Microbial Metabolic Engineering & Technology Research Center, New Drugs Research & Development Company of North China Pharmaceutical Group Corporation

.................. page:40-45

Screening of high-yield teicoplanin producing strain by Atmospheric and Room Temperature Plasma mutagenesis (常压室温等离子体诱变选育替考拉宁高产菌株)

Ren Lin-ying, Zhang Zhu-lan, Tang Wen-li, Wang De-sen, Yang Huang-jian, Qiu Guan-rong, Lian Yun-yang, Fujian Provincial Key Laboratory of Screening for Novel Microbial Products, Fujian Institute of Microbiology

.................. page:46-50

Optimizition of synthetic medium for erythromycin A production by highthroughput screening technology (运用高通量筛选技术优化红霉素A发酵的合成培养基)

Liao Jian-guo, Hong Ming, Chu Ju, The State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology

.................. page:51-58

Purification and structure elucidation of colistin E analogues (多黏菌素E类似物的纯化和结构鉴定)

Wu Yong, Zhou Meng-yi, Xue Chun-jia, Feng Jun, Shanghai Domiry Bio-tech Co., Ltd, China State Institute of Pharmaceutical Industry

.................. page:59-63

Optimization of the sustained-release tablets of doxifluridine using the Box-Behnken design and the study on the mechanism of in vitro drug release (Box-Behnken响应面法优化去氧氟尿苷缓释片处方及其体外释放机制研究)

Zhao Ke, Liu Yuan, Lai Ke, Ren Jing, Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University

.................. page:64-68

Calibration techniques and applications of antibiotic potency analyzers based on the turbidimetric method (浊度法抗生素效价测定仪的校准技术及其应用)

Ding Feng-yuan, Henan Institute of Metrology

.................. page:69-72

Analysis of the related substances in tildipirosin for injection by ultra high performance liquid chromatography coupled with hybrid quadrupole orbitrap mass spectrometry (超高效液相色谱-四级杆-静电场轨道阱高分辨液质联用解析泰地罗新注射液中的有关物质)

Yan Feng, Zhou Zhe, Huang Jia-ying, Pan Juan, Cao Ying, Li Dan-ni, Zhang Jing, Wu Jian-ping, Gu Xin, Shanghai Municipal Supervisory Institute Veterinary Drugs and Feedstuff, Thermofisher Scientific

.................. page:73-79

Study and evaluation on the applicability of different microbiological methods for miconazole nitrate (不同剂型硝酸咪康唑微生物限度检查方法适用性研究与评价)

Li Hui, Yang Xiao-li, Liang Ze-mei, Qin Ya-hong, Sheng Jin-fang, Shanxi Institute for Food and Drug Control, Xi’an Innovation College of Yan’an University, Weinan Institute for Food and Drug Control

.................. page:80-84

Molecular epidemiology and resistant mechanisms of carbapenem-resistant Klebsiella pneumoniae (碳青霉烯类耐药肺炎克雷伯菌分子流行病学及耐药机制)

Yao Xin, Feng Li, Zhu Gen-miao, Banan People’s Hospital of Chongqing

.................. page:85-90

Effects of ε-PL on growth and biofilm formation of Staphylococcus aureus (ε-聚赖氨酸对金黄色葡萄球菌生长及生物膜形成的影响)

Chen Xiao-qing, Li Ke-ke, Yu Tian, Xie Yue, Zou Feng-mei, Chen Yu-qian, Li Jun-chun, Wei Lian-hua, Chinese Medicine of Gansu University, Department of Clinical Laboratory, Gansu Provincial Hospital

.................. page:91-95

Efficacy and safety of itraconazole in the treatment of oral candidiasis:A systematic review (伊曲康唑治疗口腔念珠菌病安全性与有效性的系统评价)

Chen Zhao-yan, Zhan Mei, Tian Fang-yuan, Xu Ting, Department of Pharmacy, West China Hospital, Sichuan University

.................. page:96-102

The amelioration of co-administration of azithromycin and Zhikuoyangyinkeli on bronchiectasis rats (阿奇霉素和支扩养阴颗粒联合给药对大鼠支气管扩张模型的影响及机制)

Zhang Bang-yu, Zhao Lan, Xu Ying, The Institution for Drug Clinical Trials, Shanghai Pulmonary Hospital Affiliated Tongji University, Department of Pharmacy, Shanghai Pulmonary Hospital Affiliated Tongji University, Department of Respiratory Medicine, Shanghai Pulmonary Hospital Affiliated Tongji University, Shanghai Center for Drug Evaluation and Inspection

.................. page:103-108

The activity and quality research of liangbaijianchi tablets, the new compound preparation of kavass (口卫士新型亮白健齿片活性与质量的研究)

Li Yu-qian, Sun Jia-yin, Xiong Xiao-ping, Fan Shu-hong, Luo Ting-ting, Xu Xiao-ping, West China School of Pharmacy, Sichuan University

.................. page:109-114

zhong guo kang sheng su za zhi tou gao xu zhi (《中国抗生素杂志》投稿须知)

.................. page:115-116

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