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Application of tumor M2 pyruvate kinase and cancer antigen 19-9 in pancreatic cancer
Author(s): 
Pages: 2252-2253
Year: Issue:  20
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  丙酮酸激酶胰腺肿瘤;
Abstract: 目的:探讨肿瘤型 M2丙酮酸激酶(Tumor M2-PK, TuM2-PK)、糖类抗原 19-9(CA19-9)在胰腺癌中的表达特性.方法:采用 ELISA法分别检测 50例胰腺癌患者、 35例胰腺炎患者及 80名健康体检人血中 TuM2-PK、 CA19-9含量.结果:胰腺癌患者血中 TuM2-PK、 CA19-9值分别是(164.9± 41.3) U/mL、(630.1± 200.3) U/mL.在胰腺癌的诊断中单独检测时 TuM2-PK、CA19-9敏感性分别为 75%、74.5%,特异性分别为 90%、85%,联合测定敏感性、特异性分别达到 82.3%、 100%.结论:联合检测 TuM2-PK、CA19-9有助于提高对胰腺癌诊断的特异性和敏感性.
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