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The Effects of Mori Folium Extract Solution on Experimental Venous Thrombosis among Rats
Author(s): 
Pages: 24-25
Year: Issue:  12
Journal: CHINESE JOURNAL OF INFORMATION ON TRADITIONAL CHINESE MEDICINE

Keyword:  桑叶提取液抗凝作用血栓形成大鼠;
Abstract: 目的探讨桑叶提取液对实验性大鼠静脉血栓形成的影响.方法采用结扎大鼠腹腔主静脉造成的静脉血栓模型,观察其对纤溶、凝血等指标的影响.结果桑叶提取液能明显减轻大鼠静脉血栓重量,显著延长大鼠血浆的凝血活酶时间(APTT)、凝血酶原时间(PT)和凝血酶时间(TT),抑制纤溶酶原激活物抑制剂(PAI)的活性,同时使组织型纤溶酶原激活物(tPA)和抗凝血酶(AT-Ⅲ)的活性增强.结论桑叶提取液具有明显的抑制血栓形成作用,其抗血栓作用主要是通过抗凝血作用和纤溶系统而实现的.
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