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wei xiao bing bian shen bing huan zhe niao xing jiao yuan de bian hua ji lin chuang yi yi
Author(s): 
Pages: 1144-1145
Year: Issue:  11
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  肾疾病胶原微小病变肾病;
Abstract: 目的:探讨尿Ⅳ型胶原(Ⅳ collagen,Ⅳ-C)在微小病变肾病中的变化及临床意义.方法:76例肾病综合征患者分实验组1(微小病变肾病30例)、实验组2(系膜增生性肾炎16例、膜增生性肾炎13例、膜性肾病9例和局灶节段性肾小球硬化8例),对照组30例,用放免分析法对尿Ⅳ型胶原进行检测.结果:实验组1与对照组比较,尿Ⅳ型胶原水平轻微增高(P>0.05),实验组2与对照组,尿Ⅳ型胶原水平明显增高(P<0.001),且实验组1与实验组2,尿Ⅳ型胶原水平明显低(P<0.05).结论:尿Ⅳ型胶原水平在微小病变肾病中无明显增高,故尿Ⅳ型胶原检测可作为微小病变肾病临床鉴别诊断和疗效评估的实验室指标之一.
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