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niao zhuan hua sheng chang yin zi - 1 jian ce zai tang niao bing shen bing zhong de lin chuang yi yi
Author(s): 
Pages: 1158-1159
Year: Issue:  11
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  糖尿病肾病转化生长因子β白蛋白类;
Abstract: 目的:探讨尿转化生长因子β1(TGF-β1)对糖尿病肾病(DN)疾病进展的意义.方法:采用酶联免疫吸附法(ELISA)检测82例2型糖尿病患者和25例健康成人尿TGF-β1含量,同期测定尿微量白蛋白.3个月后观察微量白蛋白组尿TGF-β1变化.结果:糖尿病患者尿TGF-β1排泄增加,5例正常蛋白尿组糖尿病患者尿TGF-β1已增高.尿TGF-β1与尿微量白蛋白呈正相关(r=0.85).结论:尿TGF-β1是DN早期疾病进展的敏感指标,与DN的病情进展有一定关系.
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