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chong xue xing xin li shuai jie huan zhe xue jiang n- duan nao li na zuo qian ti shui ping de bian hua
Author(s): 
Pages: 1164-1165
Year: Issue:  11
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  心力衰竭充血性利钠肽;
Abstract: 目的:探讨N-端脑利钠肽前体(NT-proBNP)在充血性心力衰竭(CHF)诊断和病情评估中的应用价值.方法:采用电化学发光免疫学方法测定51例CHF患者(CHF组)和22例以呼吸困难为主诉并排除心脏疾病患者(对照组)血浆NT-proBNP浓度,超声心动图测定CHF组左室射血分数(LVEF).结果:CHF组血浆NT-proBNP浓度显著高于对照组(P<0.01);CHF组NT-proBNP浓度与NYHA心功能分级呈正相关(r=0.839,P<0.01),与LVEF呈负相关(r=-0.723,P<0.01).结论:血浆NT-proBNP水平能较好反映左室功能状态,有助于CHF的诊断和病情评估.
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