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ao ting zhi ke lu lian he bu di nai de qi wu ji zai zhi liao ke su bian yi xing xiao chuan zhong de ying yong
Author(s): 
Pages: 1203-1204
Year: Issue:  11
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  哮喘奥亭止咳露布地奈德;
Abstract: 目的:探讨奥亭止咳露联合布地奈德气雾剂在治疗咳嗽变异性哮喘(CVA)中的作用及安全性.方法:将CVA72例分为3组:奥亭+布地奈德气雾剂组30例,布地奈德气雾剂组21例,强的松组21例,分别给予相应的药物治疗28 d,观察咳嗽消失时间和支气管激发试验结果,并以积分法统计有效率和显效率,同时观察药物不良反应.结果:治疗14 d,3组总有效率分别为90.00%、90.48%和90.48%,差异无统计学意义(P>0.05);但奥亭+布地奈德气雾剂组显效率明显优于布地奈德气雾剂组(60% vs 14.29%,P<0.01),与强的松组(61.90%)相当(P>0.05).奥亭+布地奈德气雾剂组平均止咳时间(5.9±1.9)d,也与强的松组(6.8±2.2)d相当(P>0.05),但明显优于布地奈德气雾剂组(9.9±3.2)d(P<0.01).奥亭+布地奈德气雾剂组有1例(3.33%)和布地奈德气雾剂组有1例(4.76%)分别发生口腔霉菌感染和声音嘶哑,而强的松组共有8例(38.09%)出现不良反应,明显大于前两组(P<0.01).结论:奥亭止咳露联合布地奈德气雾剂是CVA既快速有效又安全的治疗新方法.
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