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Research Progress in Imidazoleglycerol Phosphate Dehydratase and its Inhibitors
Author(s): 
Pages: 433-436
Year: Issue:  10
Journal: CHINESE JOURNAL OF PESTICIDES

Keyword:  咪唑甘油磷酸酯脱水酶组氨酸生物合成三唑磷酸酯类抑制剂;
Abstract: 咪唑甘油磷酸酯脱水酶(IGPD)是植物和微生物体内组氨酸生物合成的关键酶之一,可以作为设计除草剂的靶标,通过抑制酶的活性中断组氨酸的合成使植物死亡,达到除草目的.文中介绍了IGPD的酶学特征与催化机理,并着重概述了以IGPD为靶标的三唑磷酸酯类抑制剂的研究进展.
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