Further exploration of bacterial fatal granuloma after trauma: treatment of four patients
Author(s): GAO Tian-wen, LI Chun-ying, LIU Zhong-rong, XU Xiu-li, SUN Dong-jie, QI Xian-long, LIU Bin, WANG Gang, ZHAO Xiao-dong, LI Ting-hui, FAN Ping-shen, WANG Sheng-chun, WANG Jin-cun, SHI Jian-guo, YAN Pei-song, ZHAO Gang, SUN Yi-qun, HAO Xiao-ke, DING Zhen-ruo, LIU Yu-feng
Pages: 513-516
Year: 2005 Issue: 8
Journal: JOURNAL OF CLINICAL DERMATOLOGY
Keyword: 肉芽肿; 致死性; 细菌性; 外伤后; 治疗;
Abstract: 目的:再探讨外伤后细菌性致死性肉芽肿.方法:回顾性分析4例外伤后细菌性致死性肉芽肿的临床诊治过程,根据抗生素治疗中患者皮损、颅脑磁共振成像变化及最终结果,总结该病的治疗近况,提出抢救治疗的措施.结果:从3例患者皮损中成功分离出相同的严格厌氧性多形态杆菌,根据药敏试验结果选用敏感抗生素治疗,对皮损有明显效果,但颅脑损害无改善,最终,1例无颅脑损害的患者治愈,3例伴颅脑损害的患者死亡.结论:外伤后细菌性致死性肉芽肿的治疗相当棘手,对于尚未累及颅脑的感染,林可霉素联合多西环素可作为首选.若已有颅内感染,除应用抗生素外,需积极考虑外科手术以期挽救患者生命.
Pages: 513-516
Year: 2005 Issue: 8
Journal: JOURNAL OF CLINICAL DERMATOLOGY
Keyword: 肉芽肿; 致死性; 细菌性; 外伤后; 治疗;
Abstract: 目的:再探讨外伤后细菌性致死性肉芽肿.方法:回顾性分析4例外伤后细菌性致死性肉芽肿的临床诊治过程,根据抗生素治疗中患者皮损、颅脑磁共振成像变化及最终结果,总结该病的治疗近况,提出抢救治疗的措施.结果:从3例患者皮损中成功分离出相同的严格厌氧性多形态杆菌,根据药敏试验结果选用敏感抗生素治疗,对皮损有明显效果,但颅脑损害无改善,最终,1例无颅脑损害的患者治愈,3例伴颅脑损害的患者死亡.结论:外伤后细菌性致死性肉芽肿的治疗相当棘手,对于尚未累及颅脑的感染,林可霉素联合多西环素可作为首选.若已有颅内感染,除应用抗生素外,需积极考虑外科手术以期挽救患者生命.
Citations
- 外伤后细菌性致死性肉芽肿——一种新的疾病? 高天文 中国皮肤性病学杂志
- Fatal bacteria granuloma after trauma:a new entity Gao TW Br J Dermatol
- 外伤后细菌性致死性肉芽肿的透射电镜观察 高天文 第四军医大学学报
- Delayed postoperative intracerebral abscess caused by Proprionibacterium acnes:case report and review of the literature Barazi SA Br J Neurosurg
- Focal intracranial infections due to Propionibacterium acnes:report of three cases Chu RM Neurosurgery
- Failure of intravenous antibiotic therapy of multiple temporal brain abscesses due to Propionibacterium acnes requiring temporal lobectomy Senneville E J Infect
- Propionibacterium acnes causes postoperative brain abscesses unassociated with foreign bodies:case reports Berenson CS Neurosurgery
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