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Issue:
rho dan bai yu zhong liu
Author(s):
LIU Fuzuo
,
LIU Linlin
,
XU Huimian
Pages:
493
-
496
Year:
2005
Issue:
7
Journal:
FOREIGN MEDICAL SCIENCES (ONCOLOGY SECTION)
Keyword:
G蛋白质类
;
GTP磷酸水解酶
;
脱噬作用
;
细胞周期
;
肿瘤转移
;
Abstract:
Rho蛋白(RhoGTP酶)家族与肿瘤关系密切,在其调节子和效应子作用下,影响肿瘤的发生、生长、侵袭和转移.因此Rho蛋白和它们的效应子可能是有效的抗肿瘤靶点,针对这些靶点可以研究有效的药物或基因治疗物质,干涉Rho蛋白的功能,促进肿瘤临床治疗的发展.
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