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Issue:
shou su yu zi gong nei mo yi wei zheng
Author(s):
XIAO Xiaoli
,
ZUO Demin
Pages:
303
-
306
Year:
2005
Issue:
5
Journal:
FOREIGN MEDICAL SCIENCES OBSTET GYNECOL FASCICLE
Keyword:
瘦素
;
瘦素受体
;
子宫内膜异位症
;
腹腔微环境
;
免疫调节
;
血管形成
;
Abstract:
子宫内膜异位症(EMs)是与免疫相关的慢性炎症性疾病.腹腔内异位内膜的黏着、侵袭、血管形成是EMs发生发展的基本环节.近年研究发现,瘦素作为人体内重要的激素和效应因子,具有改变腹腔微环境、促进子宫内膜基质细胞增生、调节基质金属蛋白酶及其抑制物比例、参与新生血管形成及抑制凋亡等功能.EMs时异常表达的瘦素系统在上述各环节中起着重要的调节作用,与EMs的发生发展密切相关.就瘦素在EMs中的多重调节效应进行综述.
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