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wei shi guan fan liu xing ji bing xue guan huo xing chang zuo ji shi guan chang du de yan jiu
Author(s): 
Pages: 475-476
Year: Issue:  5
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  胃食管反流血管活性肠肽腹内食管长度;
Abstract: 目的:探讨血管活性肠肽 (VIP)和食管腹内段长度 (EL)在胃食管反流病( GERD)和正常对照者中的差异性,为 GERD诊断以及寻找有价值的新方法提供理论依据.方法:采用定点牵拉方法测定下食管括约肌压力( LESP),放射免疫法测定血浆 VIP,应用体表超声仪测定空腹状态下 EL. 结果:病例组较对照组 LESP显著下降、 VIP升高、 EL缩短( P< 0.01),且 LESP与 VIP呈显著负相关,与 EL呈显著正相关( P< 0.01). 结论: GERD患者血浆 VIP浓度升高, EL缩短是 GERD发病的重要机制,体表超声检查是诊断 GERD的有效方法.
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