Effect of Composite Salviae Dropping Pill Combined with Chemotherapy in Patients with Colorectal Carcinoma
Author(s): CHEN Xiaodong, LIANG Qilian, LI Xiaoying, ZHANG Ying, LI Jianwen, LIANG Zhu
Pages: 300-302
Year: 2005 Issue: 4
Journal: CHINESE JOURNAL OF SURGERY OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE
Keyword: 大肠癌; 复方丹参滴丸; 药物治疗;
Abstract: 目的:观察复方丹参滴丸联合化疗对中晚期大肠癌疗效及生存质量的影响.方法:93例中晚期大肠癌患者随机分为滴丸化疗、单纯化疗两组,滴丸化疗组(47例)采用复方丹参滴丸加LLF方案治疗,单纯化疗组(46例)采用单纯LLF方案化疗.结果:滴丸化疗、单纯化疗两组的有效率(Complete remission+Partial ression,CR+PR)分别为51.1%和41.3%(P>0.05),临床获益率(Complete Remission+Partial Ression+Stable Disease,CR+PR+SD)分别为80.8%和58.7%(P<0.05),滴丸化疗组治疗后T淋巴细胞亚群中的CD4/CD8比值有明显提高(P<0.01),而单纯化疗组治疗前后无明显变化(P>0.05),生存质量滴丸化疗组高于单纯化疗组(P<0.05),恶心呕吐、感觉神经毒性、腹泻、白细胞减少及粘膜炎单纯化疗组高于滴丸化疗组(P<0.05).结论:复方丹参滴丸加化疗治疗大肠癌能提高患者的治疗临床获益率,改善生存质量,高患者的免疫功能和减轻化疗某些不良反应.
Pages: 300-302
Year: 2005 Issue: 4
Journal: CHINESE JOURNAL OF SURGERY OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE
Keyword: 大肠癌; 复方丹参滴丸; 药物治疗;
Abstract: 目的:观察复方丹参滴丸联合化疗对中晚期大肠癌疗效及生存质量的影响.方法:93例中晚期大肠癌患者随机分为滴丸化疗、单纯化疗两组,滴丸化疗组(47例)采用复方丹参滴丸加LLF方案治疗,单纯化疗组(46例)采用单纯LLF方案化疗.结果:滴丸化疗、单纯化疗两组的有效率(Complete remission+Partial ression,CR+PR)分别为51.1%和41.3%(P>0.05),临床获益率(Complete Remission+Partial Ression+Stable Disease,CR+PR+SD)分别为80.8%和58.7%(P<0.05),滴丸化疗组治疗后T淋巴细胞亚群中的CD4/CD8比值有明显提高(P<0.01),而单纯化疗组治疗前后无明显变化(P>0.05),生存质量滴丸化疗组高于单纯化疗组(P<0.05),恶心呕吐、感觉神经毒性、腹泻、白细胞减少及粘膜炎单纯化疗组高于滴丸化疗组(P<0.05).结论:复方丹参滴丸加化疗治疗大肠癌能提高患者的治疗临床获益率,改善生存质量,高患者的免疫功能和减轻化疗某些不良反应.
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