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The Expression of COX-1 and COX-2 Following Brain Injuries
Author(s): 
Pages: 223-225
Year: Issue:  3
Journal: JOURNAL OF FORENSIC MEDICINE

Keyword:  环加氧酶脑损伤损伤时间;
Abstract: 环加氧酶(cyclooxygenase,COX)是催化花生四烯酸(arachidonic,AA)合成前列腺素(prostaglandin,PG)的限速酶.后者在调节有丝分裂、凋亡、血管生成、血流动力学、继发性脑损伤及炎症反应等过程中发挥重要作用.COX有两种亚型:COX-1和COX-2.近年来研究证实,COX-1和COX-2在脑损伤过程中扮演了重要的角色.
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