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Application of Mismatch Negativity (MMN) in Patients with Depression
Author(s): LOU Feiying, CHEN Xingshi, ZHANG Mingdao, LIANG Jianhua, CHEN Xinwei
Pages: 16-
17,23
Year: 2005
Issue:
1
Journal: JOURNAL OF NEUROLOGY AND NEUROREHABILITATION
Keyword: 失匹配负波; 抑郁症; 正常对照组;
Abstract: 目的探讨失匹配负波(MMN)在抑郁症患者中的应用价值.方法应用美国Nicolet Bravo脑诱发电位仪对53例抑郁症和50例正常成人进行了MMN检测.结果与正常对照组相比,抑郁症患者MMN潜伏期后移(正常对照组:180.2±22.7ms,抑郁症组200.6±20.1ms,t=4.8,P<0.01),波幅降低(正常对照组4.6±2.0μV,抑郁症组3.4±1.9μV,t=3.12,P<0.01).结论 MMN技术可反映抑郁症患者诱发脑电的自动加工过程.MMN可作为抑郁症患者的临床应用检测指标.
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