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Studies on the Optimization Fermentation by Marine Micromonospora AM105 with Inhibition of MRSA
Author(s): 
Pages: 39-42
Year: Issue:  1
Journal: PHARMACEUTICAL BIOTECHNOLOGY

Keyword:  海洋小单孢菌液体发酵抗生素MRSA;
Abstract: 从南海海域红树林根际淤泥中分离获得一株能有效抑制耐甲氧西林金黄色葡萄球菌(MRSA)的海洋小单孢菌AM105.以AM105为出发菌株,对其液体发酵工艺进行了研究.实验考察了碳源、氮源、盐度、无机盐、pH值及接种量等对AM105产抗生素的影响,并通过正交实验对培养基配比进行了优化.优化发酵条件下,5L发酵罐发酵6 d时发酵液抑菌圈直径可达36.5mm.
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