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Issue:
The development of radioimmunoimaging in ovarian cacer research
Author(s):
ZOU Chunfang
Pages:
552
-
555
Year:
2004
Issue:
7
Journal:
FOREIGN MEDICAL SCIENCES (ONCOLOGY SECTION)
Keyword:
卵巢肿瘤
;
放射性免疫检测
;
抗体
;
单克隆
;
Abstract:
卵巢癌居妇科恶性肿瘤死亡率之首.放射免疫显像(RII)技术运用抗原抗体特异性结合反应与放射性同位素示踪相结合的原理,成为卵巢癌早期诊断和术后随访的灵敏度和特异性很高的一种定性影像学诊断技术.现简要介绍近年来各种单抗在卵巢癌RII中的运用,评价不同单抗诊断的准确性特异性敏感性以及不同抗体形式尤其是基因工程抗体在卵巢癌RII应用研究的进展及优缺点,并介绍RII应用预定位技术的原理及研究现状.
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