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kang zuo zuo xin yao er ke ying yong yan jiu jin zhan
Author(s): 
Pages: 330-333
Year: Issue:  6
Journal: WORLD CLINICAL DRUGS

Keyword:  癫痫抗癫痫新药药物动力学;
Abstract: 癫痫是儿童的常见病.最近几年有多种新型抗癫痫药物用于儿童癫痫的治疗.从1993年起,8种新型抗癫痫药物在美国得到应用,这8种药物(非尔氨酯,加巴喷丁,拉莫三嗪,托吡酯,噻加宾,左乙拉西坦,奥卡西平和唑尼沙胺),除左乙拉西坦和唑尼沙胺以外,用于儿童癫痫患者都已获得美国FDA批准.拉莫三嗪、托吡酯和奥卡西平在我国也已获准用于儿童癫痫患者.本文就这些可以用于儿童癫痫治疗的新型抗癫痫药物的作用机制、药物动力学特点,临床适应证、剂量和不良反应作一简单介绍.
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