The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
guan xin bing huan zhe guan mai bing bian yan zhong cheng du yu xue guan jin zhang su zhuan huan mei ji yin duo tai xing de xiang guan xing yan jiu
Author(s): 
Pages: 624-626
Year: Issue:  6
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  冠状动脉疾病多态现象(遗传学)血管紧张素转换酶冠状动脉造影;
Abstract: 目的:研究血管紧张素转换酶(ACE)基因I/D多态性与冠心病及冠脉病变严重程度的关系.方法:采用聚合酶链式反应(PCR)技术检测122例冠心病患者和80例健康人群ACE基因多态性,并对病例组进行冠状动脉造影,判定冠脉病变支数和危险记分.结果:ACE基因型分布和等位基因频率在病例组和对照组间差异有显著性,病例组DD基因型和D等位基因频率显著高于对照组(P<0.05).冠脉病变支数和危险记分在ACE基因型间差异无显著性(P>0.05).结论:ACE基因多态性中DD型和D等位基因是冠心病发病的独立危险因素,但与冠脉病变严重程度不相关.
Related Articles
No related articles found