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xiao er lang chuang shen yan yu hou fen xi
Author(s): 
Pages: 629-630
Year: Issue:  6
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  狼疮肾炎儿童;
Abstract: 目的:探讨小儿狼疮肾炎(LN)的预后相关因素.方法:对63例LN患儿采用COX比例风险模型进行生存分析.结果:本组LN患儿生存率及肾功能稳定率和国内外相仿,确诊时间的长短、病程早期是否重度活动及在进展期是否出现中枢神经系统受累是影响患儿生存率的独立因素;病程早期是否重度活动、病程早期是否有Cr升高、随访过程中是否仍存在大量蛋白尿是影响肾功能稳定率的独立因素;现行治疗方案下儿童LN治疗后出现严重并发症.结论:早期诊断、控制狼疮活动有利于预后.治疗并发症应引起重视.
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