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zuo ge lie tong zhi liao zao qi tang niao bing shen bing de lin chuang guan cha
Author(s): 
Pages: 704-705
Year: Issue:  6
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  糖尿病肾病降血糖药吡格列酮;
Abstract: 目的:观察噻唑烷二酮类(thiazo-lidinedione,TZD)胰岛素增敏剂吡格列酮对早期糖尿病肾病患者的尿蛋白排泄的影响.方法:选择58例早期糖尿病肾病患者,随机分为两组,对照组23例,给予常规降糖治疗;治疗组35例,在常规降糖治疗基础上,加用吡格列酮30 mg,每日1次口服,治疗12周,观察治疗前后尿的白蛋白排泄率、血糖、血脂、糖化血红蛋白、肾功能的变化.结果:疗程结束后,治疗组尿白蛋白排泄率明显减少,治疗前后相比及与对照组相比差异有显著性(P<0.05).结论:吡格列酮对早期糖尿病肾病有保护作用.
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