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Genetic Polymorphism of two STR Loci D2S1399 and D5S2500 in Eastern Chinese Han Population
Author(s): XIA Shuixiu, GAO Yuzhen, BIAN Shizhong, WANG Zufeng, ZHANG Zhixiang, BU Ming, ZHANG Jianhua
Pages: 200-
201,204
Year: 2004
Issue:
4
Journal: JOURNAL OF FORENSIC MEDICINE
Keyword: D2S1399; D5S2500; 遗传多态性; 法医学;
Abstract: 目的研究D2S1399和D5S2500基因座在中国华东地区汉族群体遗传多态性.方法应用PCR、聚丙烯酰胺垂直电泳及银染技术检测D2S1399和D5S2500基因座的遗传多态性.结果D2S1399和D5S2500基因座在中国华东汉族群体分别检出11个和9个等位基因,其观察杂合度(Ho)分别为0.745和0.807,多态信息含量(PIC)分别为0.850和0.750,个体识别能力(DP)分别为0.958和0.917,非父排除率(PE)分别为0.554和0.643.结论D2S1399和D5S2500两个基因座是高度多态性STR基因座,在法医学中有重要应用价值.
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