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The advance of investigation relationship between Runx3 gene and digestive system neoplasm
Author(s): 
Pages: 128-131
Year: Issue:  2
Journal: FOREIGN MEDICAL SCIENCES (ONCOLOGY SECTION)

Keyword:  肿瘤抑癌基因;
Abstract: 哺乳动物Runt domain家族包括Runx1、Runx2和Runx3三个基因,都与人类疾病的发生密切相关.最近,Runx3基因被认为是一个新的抑癌基因.在早期胃癌细胞中Runx3基因表达下调约40%,而在进展期胃癌Runy3基因表达下调几乎达到90%,因而推测Runx3基因可能是胃癌发生过程中的关键性基因.
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