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Progress of research on bikunin's inhibitory effect on metastasis of ovarian cancer
Author(s): 
Pages: 147-149
Year: Issue:  2
Journal: FOREIGN MEDICAL SCIENCES (ONCOLOGY SECTION)

Keyword:  卵巢肿瘤胰蛋白酶抑制剂肿瘤转移;
Abstract: Bikunin可以通过抑制尿激酶型纤溶酶原激活剂(uPA)、调节有关信号传导途径等机制抑制卵巢癌的浸润和转移.裸鼠体内实验已证实Bikunin的治疗作用.临床观察表明Bikunin水平与卵巢癌患者预后有关.现将Bikunin的结构和来源、抑制卵巢癌浸润及转移的机制、临床应用等相关文献综述如下.
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