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Advance in the treatment of non-Hodgkin's lymphoma with autologous stem cell transplantation plus rituximab
Author(s): 
Pages: 157-160
Year: Issue:  2
Journal: FOREIGN MEDICAL SCIENCES (ONCOLOGY SECTION)

Keyword:  造血干细胞移植自体抗体单克隆淋巴瘤非霍奇金氏;
Abstract: 经过自体干细胞移植(ASCT)治疗的非霍奇金淋巴瘤(NHL)患者仍有部分复发.复发的根源主要为体内的微小残留病变,包括体内残留的肿瘤细胞和移植物中的肿瘤细胞.单克隆抗体美罗华可通过清除CD20+B细胞而达到体内净化,预防了移植物肿瘤细胞的污染,并可进一步清除体内残留病灶.ASCT联合美罗华有望进一步提高NHL的疗效.
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