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yi bing fen fen tai ni quan ping jing mai ma zui zai lu nao shou shu zhong de lin chuang guan cha
Author(s): 
Pages: 2-3
Year: Issue:  4
Journal: THE MEDICAL JOURNAL OF INDUSTRIAL ENTERPRISE

Keyword:  全凭静脉麻醉异丙酚芬太尼颅内肿瘤切除术;
Abstract: 目的:研究异丙酚和芬太尼全凭静脉麻醉在颅内肿瘤切除术的应用及效果评价.方法:择期颅内肿瘤病人60例,随机分成静吸复合麻醉组(静吸组)和全凭静脉麻醉组(全静脉组),两组均以咪唑安定0.2mg/kg,芬太尼4ug/kg,阿曲库铵0.6mg/kg诱导后作气管插管.麻醉维持:静吸组用异氟醚为主吸入,全静脉组用微量泵注入异丙酚6mg/kg/h和芬太尼3ug/kg/h混合液.记录麻醉诱导前,切头皮,切开硬脑膜,缝合硬脑膜,术毕的SBP、DBP、HR和SPO2,停止麻醉至拔管时间,拔管时的清醒程度和随访结果.结果:两组间的拔管时间、清醒程度无显著差异,静吸组在切开硬脑膜,缝合硬脑膜时的HR、SBP、DBP及术毕HR明显高于基础值(P<0.05),而全静脉组术中无明显变化;此外,全静脉组的术后恶心、呕吐发生率明显低于静吸组.结论:异丙酚和芬太尼全凭静脉麻醉用于颅脑手术具有效果满意,血液动力学稳定,苏醒快速,术后恶心、呕吐率低等优点,且无吸入麻醉药的手术室空气污染,可供临床应用.
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