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ABO,Rh blood group genotype and antigen change after allogeneic hematopoietic stem cell transplantation
Author(s): 
Pages: 161-164
Year: Issue:  3
Journal: JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE

Keyword:  异基因造血干细胞移植基因型抗原转变;
Abstract: 目的探讨异基因外周血造血干细胞移植(Allo-PBSCT)后患者ABO、Rh血型的转变在血液病移植治疗中的意义.方法选择2例非血源关系的供、受者作为研究对象,采用基因分型与血清学方法检测移植前后ABO、Rh血型的表达,追踪移植后患者血型基因型与抗原的转变.结果 2例患者分别在移植后第7天与第10天检测到供者的A、Rh(c)基因,第7天与第15天不同程度地表达供者的ABO、Rh血型抗原.结论观察ABO与Rh血型的转变可作为植入证明的检测方法之一,且直观、迅速.
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