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The genetic polymorphism of 7 Y-STR loci and haplotype in Tibetan Population
Author(s): ZHAO Dong, WANG Baojie, DING Mei, LU Yan, SUN Dacheng, LIU Zhifang
Pages: 88-
91
Year: 2004
Issue:
2
Journal: JOURNAL OF FORENSIC MEDICINE
Keyword: Y-STR; 遗传多态性; 个人识别; 单倍型;
Abstract: 目的调查藏族Y染色体7个STR基因座及单倍型的遗传多态性.方法应用PCR、变性聚丙烯酰胺凝胶电泳结合银染显色分型技术,检测67例藏族男性DNA样品.结果在DYS393、DYS389 Ⅰ、DYS19、DYS390、DYS389Ⅱ、DYS392等6个基因座中共检出25个等位基因,DYS385基因座检出22个等位基因组,频率分布在0.0149~0.507 5之间,各基因座DP值分布在0.507 5~0.8991之间,以DYS385基因座最高.由7个基因座组成的YH6系统单倍型有51种,DP值为0.9887,DYS393与DYS389Ⅱ基因座等位基因少,推测藏族群体在进化过程中可能发生过瓶颈事件.结论上述7个STR基因座属于高鉴别能力基因座,单倍型具有很高的遗传多态性.
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