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Effect of arginine in nutritional support for malnourished patients with chronic obstructive pulmonary disease complicated with respiratory failure
Author(s): 
Pages: 91-93
Year: Issue:  2
Journal: CHINESE JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Keyword:  慢性阻塞性肺疾病精氨酸营养支持;
Abstract: 目的评价精氨酸对慢性阻塞性肺疾病(COPD)呼吸衰竭营养支持的作用.方法对30例COPD患者进行营养支持治疗10 d,总能量摄入为静息能量消耗(REE)的1.5倍,其中蛋白质占20%,脂肪30%,碳水化合物50%.12例为精氨酸组,每天减少动物蛋白质30 g,以L-精氨酸30 g替代,每次10 g,3次/d.18例为对照组,观察其效果.结果营养支持后,精氨酸组肱三头肌皮褶厚度、前白蛋白及体脂等营养参数较对照组明显改善,呼吸肌力显著提高,REE显著下降(P均<0.05).结论精氨酸不仅可改善COPD的营养状况和呼吸肌力量,且能显著降低患者的能量消耗,强化营养支持的效果,改善预后.
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