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Study on Related Substance of Sulfamethoxazole of Compound Sulfamethoxazole Oral Suspension by TLC
Author(s): 
Pages: 18-20
Year: Issue:  1
Journal: JIANGSU PHARMACEUTICAL AND CLINICAL RESEARCH

Keyword:  磺胺甲(口恶)唑混悬剂磺胺甲(口恶)唑有关物质薄层色谱法;
Abstract: 目的采用薄层色谱法对复方磺胺甲(口恶)唑混悬剂中磺胺甲(口恶)唑的有关物质进行检测.方法硅胶GF254板,展开剂为氯仿-正庚烷-乙醇(9∶9∶9,v/v).结果杂质斑点与主斑点分离良好且检测灵敏.磺胺甲(口恶)唑最低检出量为40 ng,杂质磺胺的最低检出量为20 ng,杂质对氨基苯磺酸的最低检出量为10 ng.结论本法可用于复方磺胺甲(口恶)唑混悬剂中磺胺甲(口恶)唑的有关物质的检查.
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