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New advances on hydantoinase
Author(s): 
Pages: 1-4,58
Year: Issue:  2
Journal: JOURNAL OF BIOLOGY

Keyword:  海因酶D-氨基酸;
Abstract: 海因酶在生产手性药物中间体D-氨基酸上具有广泛的应用价值.全面综述了海因酶的研究历史、分类、进化和酶学性质;总结了产海因酶的菌种筛选和产酶条件、D-海因酶的纯化、微生物海因酶基因的克隆及其在大肠杆菌中的表达等技术;阐述了酶法合成D-(-)-对羟基苯甘氨酸的工艺条件.
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