Author(s): CHEN Ping, CHEN Peizhen, YUAN Yueping
Pages: 66-68
Year: 2003 Issue:  5
Journal: JIANGSU PHARMACEUTICAL AND CLINICAL RESEARCH
Keyword:  阿米替林; 左旋四氢巴马汀; 镇痛作用; 热板法; 化学刺激法;
Abstract: 目的探讨阿米替林增强左旋四氢巴马汀(L-THP)的镇痛作用.方法采用热板法和化学剌激法进行镇痛实验.结果阿米替林两组剂量(4.2 mg/kg , 8.3 mg/kg)均加强了L-THP的镇痛作用,镇痛作用时间持续4 h.结论阿米替林可增强L-THP的镇痛作用.