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Association of Mycoplasma genitalium and Ureaplasma urealyticum with nongonococcal urethritis
Author(s): 
Pages: 85-88
Year: Issue:  2
Journal: CHINA JOURNAL OF LEPROSY AND SKIN DISEASES

Keyword:  生殖支原体解脲脲原体非淋菌性尿道炎;
Abstract: 目的:研究生殖支原体(Mg)及解脲脲原体(Uu)与男性急性非淋菌性尿道炎(NGU)的相关性.方法:采用病例对照研究,收集性病门诊NGU病人、性病门诊有非婚性行为但无尿道炎的就诊者及健康体检者三组人群的尿道拭子,用AMPLICORCT/NG PCR Test进行沙眼衣原体(Ct)的检测,巢式PCR(nPCR)和培养法进行Uu、人型支原体(Mh)的检测,nPCR及扩增产物DNA测序进行Mg的检测.结果:三组人群中Mg的检出情况分别为:25例(25%)、6例(6.4%)和0(P<0.0001),其中6例NGU病人为Ct与Mg混合感染.在NGU和门诊对照组中,Mg阳性者罹患急性NGU的危险性是Mg阴性者的3.917倍,(95%CI:1.618~9.126);在Ct阴性的NGU(NCNGU)中,Mg感染使罹患急性NGU的危险性增加7.2倍(95%CI:2.9~18.0).nPCR检出三组人群中Uu的携带者分别为:40例(40%)、42例(44.7%)和46例(46.9%).结论:Mg感染与男性急性NGU呈强相关,Uu与NGU无相关性.
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