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Column-Switching High-performance Liquid Chromatography and Its Application in Biopharmaceutical Analysis
Author(s): 
Pages: 274-278
Year: Issue:  5
Journal: PROGRESS IN PHARMACEUTICAL SCIENCES

Keyword:  柱切换HPLC在线浓缩净化联用技术体内药物分析;
Abstract: 综述了柱切换HPLC技术及其与在线透析、在线衍生化等联合应用于体内药物分析,以及在在线去蛋白、全血直接进样、在线浓缩净化等方面的应用情况.由于该技术最显著的特点是在线分离,增强了色谱的选择性,使之成为药物分析的强有力的工具,具有广阔的应用前景.
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