The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit
later.
We apologize for any inconvenience caused
The effects of different anaesthesia on serum catechlomine and IL-6 in breast cancer patients
Author(s): YI WEN-BO, ZHANG Jian-min
Pages: 113-
114,117
Year: 2005
Issue:
2
Journal: CHINESE JOURNAL OF CURRENT ADVANCES IN GENERAL SURGERY
Keyword: 乳腺肿瘤·麻醉; 全身·麻醉; 硬膜外·儿茶酚胺类·白细胞介素6;
Abstract: 目的: 观察乳腺癌手术时全麻复合硬膜外麻醉(GEA)和单纯全麻(GA)围手术期血清儿茶酚胺和IL-6的变化,评价其对手术应激反应的影响.方法:将40例乳腺癌手术病人随机分为GEA和GA两组,于手术前、切皮后30min、120min、术后第1、3日晨采血测定血清儿茶酚胺和IL-6的浓度.结果:两组病人血清去甲肾上腺素(NE)、肾上腺素(E)、多巴胺(DA)、儿茶酚胺总量(CA)切皮后30min升高,手术120min达高峰,术后第1日清晨依然高于手术前(P<0.05).手术切皮30min、120min时,血清儿茶酚胺总量(CA)GA组比GEA组明显偏高(P<0.05).血清IL-6手术120min时达到高峰,术后第1日仍高于手术前(P<0.05),但各时点差异无统计学意义(P>0.05).结论: 乳腺癌手术引起的儿茶酚胺升高,全麻复合硬膜外麻醉对此有一定的抑制作用,但对手术引起的细胞因子水平的改变无影响.
Citations
No citation found