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Seven Y-specific loci haplotypes and their usefulness in forensic casework
Author(s): LIU Qiuling, LV Dejian, CHEN Lizuo, TONG Dayue, LU Huiling, WU Xinyao
Pages: 196-
198,200
Year: 2003
Issue:
4
Journal: JOURNAL OF FORENSIC MEDICINE
Keyword: Y-STR; 单倍型; 复合扩增;
Abstract: 目的调查7个Y-STR基因座单倍型及其法医学应用.方法利用二组复合扩增体系,(I:DYS391、GATA-A4、GATA-A10和GATA-H4;Ⅱ:DYS439、DYS437和DYS434)检测7个Y染色体特异性的STR基因座,并用聚丙烯酰胺凝胶电泳和银染显色技术进行基因分型.结果在广东汉族372名无关男性个体中,二组7个基因座分别检出5、7、6、5和6、4、4个等位基因,共检出254种单倍型,其中201种为唯一的.单倍型基因多样性为0.9960.结论7个Y-STR基因座具有很高的识别能力,对建立Y染色体STR数据库,研究群体遗传学和进行法医学鉴定有重要意义.
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