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Experimental Study of Bitongxiao Granules in the Treatment of Prolapse of Lumbar Intervertebral Disc
Author(s): 
Pages: 12-14
Year: Issue:  4
Journal: JOURNAL OF HENAN UNIVERSITY OF CHINESE MEDICINE

Keyword:  腰椎间盘突出症痹痛消颗粒实验研究痹证;
Abstract: 目的:研究痹痛消治疗腰椎间盘作用的机制.方法:将小鼠分为生理盐水组、阿司匹林组、痹痛消低、中、高剂量组,观察痹痛消的镇痛作用和对小鼠耳廓肿胀的影响;将大鼠分为生理盐水组、阿司匹林组、痹痛消中高剂量组,观察痹痛消对大鼠足跖肿胀的影响;将大鼠分为正常对照组、空白对照组、阿司匹林组、痹痛消颗粒组,在不同时间观察痹痛消对化学性神经根炎模型的影响.结果:痹痛消镇痛明显,能抑制小鼠耳廓肿胀和大鼠足跖肿胀,作用持久显著,可抑制化学性神经根炎模型大鼠炎性肉芽肿的形成,降低模型大鼠的全血粘度、血浆粘度、红细胞聚积指数.结论:痹痛消颗粒是通过抗炎、镇痛、改善血液循环对腰椎间盘起综合治疗作用的.
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