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The effect of selectin and its ligands on tumor metastasis
Author(s): 
Pages: 274-277
Year: Issue:  3
Journal: PROGRESS OF ANATOMICAL SCIENCES

Abstract: 选择蛋白(selectin)在生理状态下参与白细胞运行过程的调节,在炎症反应过程中与白细胞的渗出密切相关.近期研究发现,在肿瘤的转移过程中,选择蛋白及其配体也可发挥重要的作用,甚至是导致肿瘤发生转移的信号分子之一,而阻断选择蛋白及其配体间的相互作用有可能抑制肿瘤转移的发生.
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