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zhi qi guan guan xi ye he xue qing scc cea cyfra21-1 jian ce dui fei ai zhen duan jia zhi de tan tao
Author(s): 
Pages: 254-255
Year: Issue:  3
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  肺肿瘤癌胚抗原鳞状细胞癌抗体细胞角蛋白19片段支气管肺泡灌洗液;
Abstract: 目的:探讨支气管灌洗液(BLF)和血清鳞状细胞癌抗体(SCC)、癌胚抗原(CEA)、细胞角蛋白19片段(CYFRA21-1)联合检测对肺癌的诊断价值.方法:SCC、CEA、CYFRA21-1测定采用ELISA方法.标本取自48例肺癌病人和35例非肺癌病人的支气管灌洗液和血清.结果:肺癌患者BLF中测定SCC、CEA、CYFRA21-1的敏感性分别为95.8%、56.3%、83.3%,肺癌组SCC、CEA、CYFRA21-1水平明显高于非肺癌组(P<0.01).肺癌患者血清SCC、CEA、CYFRA21-1的敏感性分别为20.8%、77.1%、66.7%,肺癌组CEA、CYFRA21-1水平明显高于非肺癌组(P<0.01),血清SCC两组间无明显差异(P>0.05),BLF和血清SCC、CEA、CYFRA21-1联合检测的敏感性为100%.结论:BLF和血清SCC、CEA、CYFRA21-1联合检测对肺癌诊断有重要价值.
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