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yi tuo zuo zuo yu yi bing fen zai quan ma you dao cha guan shi xin lv bian yi xing he xue tang de bian hua
Author(s): 
Pages: 258-259
Year: Issue:  3
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  异丙酚依托咪酯血糖心率;
Abstract: 目的:旨在观察依托咪酯与异丙酚在全麻诱导插管时心率变异性和血糖的变化.方法: 选择ASAⅠ~Ⅱ级,开腹行胆囊切除或并胆总管探查术患者40例,均无糖尿病病史,分为两组,E组:依托咪酯0.3 mg/kg,P组:异丙酚2 mg/kg.应用HXD-Ⅰ型多功能监测仪记录各参数.用血糖仪监测血糖.结果:插管前两组SBP、DBP、HR均显著降低(E组P<0.05,P组P<0.01),两组HF、LF/HF,P组LF显著降低(P<0.05),两组血糖较诱导前基础值T1(T0)降低有显著意义(P<0.01),插管后两组SBP、DBP、HR、HF、LF/HF均显著升高(P<0.01), P组LF显著升高(P<0.05).组间比较插管前SBP、DBP、HR、LF、HF、LF/HF降低P组较E组明显(P<0.01).结论:依托咪酯在麻醉诱导后降低血压和抑制自主神经功能的作用明显弱于异丙酚,但抑制气管插管所致的心血管反应、应激时血糖的变化,两种药物无显著差异.
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