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High dosage Oryzanol and Vitamin B1 in the treatment of functional dyspepsia
Author(s): 
Pages: 280-281
Year: Issue:  3
Journal: ANTHOLOGY OF MEDICINE

Keyword:  功能性消化不良抑郁症谷维素维生素B1;
Abstract: 目的探讨大剂量谷维素和维生素B1对功能性消化不良(FD)及患者情绪障碍的疗效.方法选取符合"罗马标准"确诊为FD,同时伴有明显的抑郁及焦虑情绪的患者86例随机分为治疗组和对照组,对照组根据治疗个体化原则选用吗丁啉、雷尼替丁、硫糖铝或铝碳酸镁等常规治疗.治疗组除上述常规治疗外,还予以心理疏导及大剂量谷维素和维生素B1各100mg,3次/d,8周为1个疗程.根据症状积分变化评定疗效.结果治疗组治疗8周后的显效率和总有效率分别为65.1%和86.0%,而对照组则为51.1%和67.4%.经统计学处理,两组的显效率差异无显著性(P>0.05),而总有效率差异有显著性(P<0.05).结论大剂量谷维素和维生素B1联合心理及常规药物治疗伴有抑郁和焦虑情绪的FD患者,能够促进临床症状缓解,精神状态的改观,而且不因加大用药量而出现其它副反应.
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