Preliminary experience of Pipeline Flex device in the treatment of intracranial aneurysms
Author(s): Wang Kai, Cheng Xiaojiang, Kaheerman · Kadeer, Maimaitili · Aisha
Pages: 547-551
Year: 2019 Issue: 6
Journal: Chinese Journal of Neurosurgery
Keyword: Intracranial aneurysm; Embolization; therapeutic; Embolization device;
Abstract: Objective To explore the clinical application and preliminary experience of Pipeline Flex device (PED Flex) in the treatment of intracranial aneurysms.Methods The data of 23 patients with 23 intracranial aneurysms treated by Pipeline Flex device at Neurosurgery Department of the First Affiliated Hospital of Xinjiang Medical University from January to November 2018 were retrospectively analyzed.Among them,4 were ruptured aneurysms and 19 were unruptured aneurysms.There were 20 anterior circulation aneurysms and 3 posterior circulation aneurysms.The size of aneurysm was 7.2-30.2 mm,with an average of 15.7 ± 6.3 mm.There were 19 cases of cystic aneurysm,2 cases of fusiform aneurysm and 2 cases of dissecting aneurysm.Among all cases,13 were treated with adjuvant coils.Results PED Flex stent was successfully implanted in 21 (91％) cases.The stents adhered well after release and no balloon was used for post-dilatation.PED failed to be placed in 2 cases including 1 with severe distortion of the proximal vessel of the parent artery and the other with intraoperative bleeding resulting in death at 5 days post operation.One patient had obstructive hydrocephalus after operation due to rupture of aneurysm before operation.The remaining patients had no perioperative complications.Six months after operation,16 patients were followed up by digital subtraction angiography (DSA).All the aneurysms were occluded well without recurrence and the parent artery was unobstructed.Conclusions The preliminary results of PED Flex in the treatment of intracranial aneurysms show that the success rate of implantation seems higher and the complications are relatively less.The short-term effect is better and long-term effect needs further follow-up.
Pages: 547-551
Year: 2019 Issue: 6
Journal: Chinese Journal of Neurosurgery
Keyword: Intracranial aneurysm; Embolization; therapeutic; Embolization device;
Abstract: Objective To explore the clinical application and preliminary experience of Pipeline Flex device (PED Flex) in the treatment of intracranial aneurysms.Methods The data of 23 patients with 23 intracranial aneurysms treated by Pipeline Flex device at Neurosurgery Department of the First Affiliated Hospital of Xinjiang Medical University from January to November 2018 were retrospectively analyzed.Among them,4 were ruptured aneurysms and 19 were unruptured aneurysms.There were 20 anterior circulation aneurysms and 3 posterior circulation aneurysms.The size of aneurysm was 7.2-30.2 mm,with an average of 15.7 ± 6.3 mm.There were 19 cases of cystic aneurysm,2 cases of fusiform aneurysm and 2 cases of dissecting aneurysm.Among all cases,13 were treated with adjuvant coils.Results PED Flex stent was successfully implanted in 21 (91％) cases.The stents adhered well after release and no balloon was used for post-dilatation.PED failed to be placed in 2 cases including 1 with severe distortion of the proximal vessel of the parent artery and the other with intraoperative bleeding resulting in death at 5 days post operation.One patient had obstructive hydrocephalus after operation due to rupture of aneurysm before operation.The remaining patients had no perioperative complications.Six months after operation,16 patients were followed up by digital subtraction angiography (DSA).All the aneurysms were occluded well without recurrence and the parent artery was unobstructed.Conclusions The preliminary results of PED Flex in the treatment of intracranial aneurysms show that the success rate of implantation seems higher and the complications are relatively less.The short-term effect is better and long-term effect needs further follow-up.
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