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Clinical Observation on the Efficacy of Ivermectin in the Treatment of Intestinal Nematode Infections
Author(s): 
Pages: 113-115
Year: Issue:  2
Journal: CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES

Keyword:  伊维菌素蛔虫钩虫鞭虫蛲虫临床观察;
Abstract: 目的观察伊维菌素驱治肠道线虫感染的效果及副作用.方法用伊维菌素0.1、0.2、0.2和0.2 mg/k顿服分别治疗蛔虫、钩虫、鞭虫和蛲虫感染者,并与阳性对照药阿苯达唑400 mg顿服进行比较.结果随机双盲治疗,伊维菌素和阿苯达唑对蛔虫感染的虫卵阴转率均为100%(34/34),对钩虫感染的虫卵阴转率分别为17.6%(6/34)和76.5%(26/34),对鞭虫感染的虫卵阴转率分别为67.6%(23/34)和47.1%(16/34),对蛲虫感染的虫卵阴转率分别为58.8%(20/34)和100%(34/34).服药后1~2 d排虫达高峰.不良反应发生率低,血液学、肝肾功能和心电图检查无明显影响.结论伊维菌素治疗鞭虫感染疗效优于阿苯达唑,治疗蛔虫感染疗效与阿苯达唑相同,治疗钩虫、蛲虫感染疗效不及阿苯达唑.
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