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The Role of Tumor-associated Macrophages in Tumor Invasion and Metastasis
Author(s): CHEN Yong, LIAO Zi-jun, XU Rui
Pages: 897-
900
Year: 2019
Issue:
5
Journal: Labeled Immunoassays and Clinical Medicine
Keyword: 肿瘤相关巨噬细胞; 肿瘤微环境; 肿瘤转移;
Abstract: 肿瘤相关巨噬细胞(tumor-associated macrophages,TAMs)是肿瘤免疫微环境中重要组成部分,主要分为M1、M2两种表型.在多数肿瘤组织中肿瘤相关巨噬细胞以M2型为主,其可与肿瘤细胞相互作用,促进肿瘤生长和转移,且具有抗肿瘤潜能和潜在的治疗价值.因此,深入了解肿瘤相关巨噬细胞,有助于更进一步探索其临床价值.本文从肿瘤相关巨噬细胞的起源和特点,以及对肿瘤发生发展作用作一综述.
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