Author(s): CHEN Wanying, WU Haiqin, FAN Jiaxin, Department of Neurology, The Second Affiliated Hospital of Xi’an Jiaotong University
Pages: 493-495
Year: 2019 Issue:  6
Journal: Journal of Apoplexy and Nervous Diseases
Keyword:  Acute cerebral infarction; Erythropoietin; Hemorheology;
Abstract: Objective To study the correlation between blood EPO and hemorheology in patients with acute cerebral infarction. Methods 90 patients with acute cerebral infarction in our hospital( cerebral infarction group) were collected,and 55 patients without cerebrovascular disease in the same period( control group) were selected. EPO and hemorheology of the two groups were compared. The correlation between EPO and hemoglobin,erythrocyte and hemorheology were analyzed in two groups respectively. Results There were significant differences in EPO and hemorheology between the two groups( P <0. 05). There were no correlation between EPO and hemorheology in the control group( P > 0. 05). However,In the cerebral infarction group EPO was positively correlated with plasma viscosity( r = 0. 373),erythrocyte sedimentation rate( r = 0. 459)and erythrocyte sedimentation equation K( r = 0. 282)( P < 0. 05). In the cerebral infarction group EPO were negative correlated with hemoglobin( r =-0. 589),erythrocyte( r =-0. 410),erythrocyte specific volume(-0. 547),whole blood viscosity shear rate of 1. 00 L/s(-0. 400),whole blood viscosity shear rate of 5. 00 L/s(-0. 361),whole blood viscosity shear rate of 30. 00 L/s( r =-0. 408),whole blood viscosity shear rate of 200. 00 L/s(-0. 300),and hematocrit(-0. 502)( P < 0. 05). Conclusion There are abnormal indexes of hemorheology in patients with acute cerebral infarction.EPO is increased In patients with acute cerebral infarction. Increased EPO can increase blood viscosity,but not by promoting the production of red blood cells.