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The Effect of Waring Yang to Promote Blood Circulation-WYRT on the Levefs of IL-4 and IgE in Nephrotic Rat Iuduced by Adriamycin Adriamycin-Induced Nephrotic Syndrome
Author(s): 
Pages: 77-78
Year: Issue:  2
Journal: CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN NEPHROLOGY

Keyword:  微小病变肾病模型温阳活血方白细胞介素-4免疫球蛋白IgE尿蛋白;
Abstract: 目的:探讨肾病综合征与白细胞介素-4(IL-4)及过敏反应的关系,以推断温阳活血方治疗原发性肾病综合征的可能作用机制.方法:用阿霉素(ADR)诱导一种类似人类微小病变肾病模型,选用温阳活血方进行治疗,并设空白、病理及强的松对照组,观测尿蛋白、血清IL-4和IgE等含量的变化.结果:造模组IL-4高于正常组,温阳活血方及强的松均有降低血清IL-4的作用,且IL-4与同期尿蛋白呈直线正相关.IgE改变无统计学差异.结论:温阳活血方减轻肾病模型尿蛋白的作用可能与降低血清IL-4水平有关.
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