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Effect of Oryzanol on Anxiety and Depression in Patients with Cerebral Infarction
Pages: 68-69+73
Year: Issue:  8
Journal: Chinese Journal of Rational Drug Use

Keyword:  OryzanolCerebrovascular DiseaseAnxietyDepressionClinical Efficacy;
Abstract: Objective: To investigate the effect of oryzanol on anxiety and depression in patients with cerebral infarction. Methods: 62 cases of patients with cerebral infarction complicated with anxiety and depression admitted to our hospital from January 2016 to January 2017 were selected as subjects and divided into control group and treatment group according to different treatment methods, 31 cases in each group. The patients in the control group were given conventional therapy. The patients in the treatment group was treated with oryzanol tablet(20 mg, tid) on the basis of the control group. The changes of anxiety and depression and the clinical effects in the two groups were observed before and after treatment. Results: Before treatment, there was no significant difference in Hamilton anxiety scale(HAMA) and Hamilton depression scale(HAMD) scores between the two groups(P>0.05). After treatment, the scores of HAMA and HAMD in the treatment group were significantly lower than those in the control group(P<0.05). The total effective rate in the treatment group was 96.77%, which was significantly higher than 80.66% in the control group(P<0.05). Conclusion: Oryzanol can effectively improve anxiety and depression after cerebral infarction and play an important role in promoting disease rehabilitation and improving the quality of life, which is worthy of clinical application.
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