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Determination of cellular immunity function and serum cytokine in patients with acute pancreatitis and its clinic significance
Author(s): 
Pages: 37-38
Year: Issue:  1
Journal: HEILONGJIANG MEDICINE AND PHARMACY

Keyword:  急性胰腺炎免疫学细胞因子;
Abstract: 目的:观察急性胰腺炎病人细胞免疫功能、血清中细胞因子的变化,探讨他们在急性胰腺炎发病机理中的作用.方法:采用流式细胞仪,测定急性胰腺炎病人T淋巴细胞亚群,采用酶联免疫吸附实验测定急性胰腺炎病人血清中IL-2、IL-8.结果:T淋巴细胞亚群中CD4阳性细胞百分比和CD4/CD8比值在急性胰腺炎病人中降低,IL-2、在急性胰腺炎病人中降低、IL-8在急性胰腺炎病人中增高.结论:急性胰腺炎症过程中存在细胞免疫功能低下,且有多种细胞因子参与其发病机理,某些细胞因子的升高与疾病的严重程度相关.
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